Q: If I test one puppy in a litter for the MDR1 genotype do I need to test other puppies?
A: See table.
Q: If I know the MDR1 genotype of the parents, do I need to test the puppies?
A: See table.
| Dam's MDR1 genotype | Sire's MDR1 genotype | Litter's MDR1 genotype possibilities |
|---|---|---|
| MDR1 mutant/mutant | MDR1 mutant/mutant | -100% of puppies MDR1 mutant/mutant |
| MDR1 mutant/mutant | MDR1 mutant/normal | -50% of puppies MDR1 mutant/mutant -50% of puppies MDR1 mutant/normal |
| MDR1 mutant/mutant | MDR1 normal/normal | -100% of puppies MDR1 mutant/normal |
| MDR1 mutant/normal | MDR1 mutant/mutant | -50% of puppies MDR1 mutant/mutant -50% of puppies MDR1 mutant/normal |
| MDR1 mutant/normal | MDR1 mutant/normal | -25% of puppies MDR1 mutant/mutant -50% of puppies MDR1 mutant/normal -25% of puppies MDR1 normal/normal |
| MDR1 mutant/normal | MDR1 normal/normal | -50% of puppies MDR1 mutant/normal -50% of puppies MDR1 normal/normal |
| MDR1 normal/normal | MDR1 mutant/mutant | -100% of puppies MDR1 mutant/normal |
| MDR1 normal/normal | MDR1 mutant/normal | -50% of puppies MDR1 mutant/normal -50% of puppies MDR1 normal/normal |
| MDR1 normal/normal | MDR1 normal/normal | -100% of puppies MDR1 normal/normal |