Submission of UGT sequences for naming
1. Only amino acid (cDNA) sequences obtained from sequencing mRNA (such as by cDNA cloning, RT-PCR, or RNAseq) can be named. mRNA sequences obtained solely by gene prediction computer software from genome sequences are not sufficient .
2. Submitted sequences must contain the conserved UGT protein sequence domain. This can be checked at this web site: http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi.
3. At least 200 amino acid residues (minimum) must be submitted to enable unambiguous comparisons with existing UGT sequences.
4. Organism genus and species (and/or common name) information must be provided to facilitate analysis using the appropriate Kingdom group and to differentiate allelic variants (same species) from orthologous genes (different species).
Format for submission
Please download the UGT Sequence Submission Form and provide the following information (corresponding to the columns):
1. *A temporary unique name for each UGT (<10 characters; no spaces; GT1, GT2, GT3.... for example)
2. *Organism scientific and/or common name
3. Nucleotide ID (Genbank number) if known
4. Protein ID (Genbank number) if known
5. Submitter name
6. Submission date
7. Any comments
8. *Amino acid sequence (in one cell - no spaces - no stop codon)
Leave cell empty if any information is unknown.
Submit sequences by email
Send file with a brief request message to Dr Michael Court
You will normally receive an acknowledgement of receipt within ~2 working days.
Most requests are completed within 1 to 2 weeks. For a large number of sequences (>20) it will take longer.
Please note that this is done on a volunteer basis as a service to the scientific community and so your patience is greatly appreciated.